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| 产品名称 | β-Catenin Rabbit Polyclonal Antibody | 反应种属 | H,M,R |
| 应用 | WB,IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | beta catenin,b-catenin,CTNB1,CTNNB1,FLJ25606,OTTHUMP00000162082 | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:1,000 IHC 1:500-1,000 | ||
| 特异性 | Antibody can detect endogenous B-Catenin proteins. | ||
| 背景信息 | The distinct peripheral cytosolic proteins,alpha,beta and gamma catenin (102,94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. | ||
| 分子量 | 92KD | 同型 | IgG1 |
| GeneID | 1499 | 理论分子量 | 92KD |
| SWISS | P35222 | 宿主物种 | Rabbit |
| 免疫原 | Recombinant Protein | 克隆性 | Polyclonal |
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Western blot analysis of 1)3T3, 2)Rat Liver, with β-Catenin Rabbit pAb diluted at 1:2,000.
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Immunohistochemical analysis of paraffin-embedded Human breast caricnoma using β-catenin Rabbit pAb diluted at 1:500.