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| 产品名称 | EGFR Mouse Monoclonal Antibody(M6) | 反应种属 | H |
| 应用 | WB,IHC,IF,IP | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | Epidermal growth factor receptor antibody,erbb 1 antibody,Receptor tyrosine protein kinase ErbB 1 antibody | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:1,000-3,000 IHC 1:100-200 IF 1:100-200 IP 1:200 | ||
| 特异性 | Antibody can detect endogenous EGFR proteins. | ||
| 背景信息 | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF,TGFA/TGF-alpha,amphiregulin,epigen/EPGN,BTC/betacellulin,epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. | ||
| 分子量 | 170KD | 同型 | IgG1 |
| GeneID | 1956 | 理论分子量 | 170KD |
| SWISS | P00533 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Western blot analysis of 1)A431 ,2)Hela, with EGFR Mouse Monoclonal Antibody diluted at 1:2,000.
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IF analysis of Hela with EGFR Mouse Monoclonal Antibody(M6)(Left) and DAPI (Right) diluted at 1:100.