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| 产品名称 | CDK5 Mouse Monoclonal Antibody(3D1) | 反应种属 | H,M,R |
| 应用 | WB,IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | CDKN5,Cyclin-dependent kinase 5,Cell division protein kinase 5,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:1,000-2,000 IHC 1:200-500 | ||
| 特异性 | Antibody can detect endogenous CDK5 proteins. | ||
| 背景信息 | cyclin dependent kinase 5(CDK5) Homo sapiens This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family,the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein,which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons,functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization,endocytosis and exocytosis,and apoptosis. In humans,an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. | ||
| 分子量 | 33KD | 同型 | IgG1 |
| GeneID | 1020 | 理论分子量 | 33KD |
| SWISS | Q00535 | 宿主物种 | Mouse |
| 免疫原 | Recombinant Protein | 克隆性 | Monoclonal |
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Western blot analysis of 1)Hela Cell,2)Jurkat Cell,3)Mouse Brain Tissue, 4)Rat Brain Tissue Lysate using CDK5 Mouse Monoclonal antibody diluted at 1:2,000
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Immunohistochemical analysis of paraffin-embedded Human BrainTissue using CDK5 Mouse Monoclonal antibody diluted at 1:200.