产品名称 |
STIP1/HOP Rabbit Polyclonal Antibody |
反应种属 |
H,M,R |
应用 |
WB |
配方 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
别称 |
Hop,HSC70/HSP90 organazing protein,p60,HELS 94n,STI1,STIP1,Stress induced phosphoprotein 1 |
储存 |
Store at -20°C. Stable for one year from the date of shipment. |
推荐稀释比 |
WB 1:2,000-5,000 |
特异性 |
Antibody can detect endogenous STIP1/HOP proteins. |
背景信息 |
Stress induced phosphoprotein 1(STIP1) Homo sapiens STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90,suggesting that it regulates both the conformations and ATPase cycles of these chaperones. |
分子量 |
64KD |
同型 |
IgG |
GeneID |
10963 |
理论分子量 |
~64KD |
SWISS |
P31948 |
宿主物种 |
Rabbit |
免疫原 |
Recombinant Protein |
克隆性 |
Polyclonal |