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| 产品名称 | P27 Kip1 Mouse Monoclonal Antibody(1A7) | 反应种属 | H,M,R |
| 应用 | WB | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | CDKN1B,CDKN4,Kip1,p27,Cyclin dependent kinase inhibitor 1b | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:2,000-5,000 | ||
| 特异性 | Antibody can detect endogenous P27 Kip1 proteins. | ||
| 背景信息 | Cyclin dependent kinase inhibitor 1B(CDKN1B) Homo sapiens This gene encodes a cyclin-dependent kinase inhibitor,which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes,and thus controls the cell cycle progression at G1. The degradation of this protein,which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes,is required for the cellular transition from quiescence to the proliferative state. | ||
| 分子量 | 27KD | 同型 | IgG1 |
| GeneID | 1027 | 理论分子量 | 27KD |
| SWISS | P45627 | 宿主物种 | Mouse |
| 免疫原 | Recombinant Protein | 克隆性 | Monoclonal |
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Western blot analysis of 1)MCF7 Cell, 2)HepG2 Cell, 3) C2C12 Cell Lysate using p27 Kpi1 Mouse Monoclonal mAb diluted at 1:2,000.