产品名称 |
SMAD7 Mouse mAb(3E3) |
反应种属 |
H,M,R |
应用 |
WB,IHC |
配方 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
别称 |
SMAD7 MADH7 MADH8 |
储存 |
Store at -20°C. Stable for one year from the date of shipment. |
推荐稀释比 |
WB 1:1,000-2,000 IHC 1:200-500 |
特异性 |
Antibody can detect endogenous SMAD7proteins. |
背景信息 |
SMAD family member 7(SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding,this complex translocates to the cytoplasm,where it interacts with TGF-beta receptor type-1 (TGFBR1),leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. |
分子量 |
46KD |
同型 |
IgG1 |
GeneID |
4092 |
理论分子量 |
46KD |
SWISS |
P49841 |
宿主物种 |
Mouse |
免疫原 |
Recombinant Protein |
克隆性 |
Monoclonal |