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| 产品名称 | CA IX Carbonic Anhydrase IX Mouse Monoclonal Antibody(12F10) | 反应种属 | H |
| 应用 | WB,IHC,IP | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | N/A | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:3,000 IHC 1:100-200 IP:1:200 | ||
| 特异性 | Antibody can detect endogenous CA IX proteins. | ||
| 背景信息 | The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa),a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore,recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors. | ||
| 分子量 | 35-58KD | 同型 | IgG1 |
| GeneID | 768 | 理论分子量 | 35-38KD |
| SWISS | Q16790 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Western blot analysis of 1)Hela, 2)293T, with CA IX Mouse mAb diluted at 1:5,000.
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Immunohistochemical analysis of paraffin-embedded Human Lung Caricnoma using CA IX/Carbonic Anhydrase IX Mouse mAb diluted at 1:200.