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| 产品名称 | CDX2 Mouse Monoclonal Antibody (14H6) | 反应种属 | H,M,R |
| 应用 | WB,IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | N/A | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:1000 IHC 1:200 | ||
| 特异性 | Antibody can detect endogenous CDX2 proteins. | ||
| 背景信息 | CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine,from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer,while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20. | ||
| 分子量 | 42KD | 同型 | IgG1 |
| GeneID | 1045 | 理论分子量 | 42KD |
| SWISS | Q99626 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Western blot analysis of 1)293T, 2)Mouse Heart tissue with CDX2 mAb diluted at 1:2,000.
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IHC staining of Human rectal cancer tissue with CDX2 mouse mAb diluted at 1:200.