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说明书下载产品属性/ Product Details
| 产品名称 | COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody | 反应种属 | H |
| 应用 | WB,IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | N/A | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:1,000 IHC 1:100 | ||
| 特异性 | Antibody can detect endogenous COX1 proteins. | ||
| 背景信息 | Cyclooxygenase-1 (COX-1),also known as prostaglandin G/H synthase 1,prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1,is an enzyme that in humans is encoded by the PTGS1 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described. | ||
| 分子量 | 70KD | 同型 | IgG |
| GeneID | 5742 | 理论分子量 | 70KD |
| SWISS | P23219 | 宿主物种 | Rabbit |
| 免疫原 | Synthetic Peptide | 克隆性 | Polyclonal |
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Western blot analysis of Hela with COX1 Rabbit Polyclonal antibody diluted at 1:1,000.