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| 产品名称 | CD45 Mouse Monoclonal Antibody (12A9) | 反应种属 | H |
| 应用 | WB,IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | N/A | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:2,000 IHC 1:200 | ||
| 特异性 | Antibody can detect endogenous CD45 proteins. | ||
| 背景信息 | CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction,inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45. | ||
| 分子量 | 147KD | 同型 | IgG1 |
| GeneID | 5788 | 理论分子量 | 147KD |
| SWISS | P06800 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Western blot analysis of Hela with CD45 mAb diluted at 1:2,000.