产品名称 |
ATG4a Rabbit Polyclonal Antibody(F303) |
反应种属 |
H,M,R |
应用 |
IHC |
配方 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
别称 |
Apg4a,Atg4al,Autl2,Cysteine protease ATG4A antibody |
储存 |
Store at -20°C. Stable for one year from the date of shipment. |
推荐稀释比 |
IHC 1:100-200 |
特异性 |
Antibody can detect endogenous ATG4a proteins. |
背景信息 |
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems,Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE),which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described,including three Atg8 proteins (GATE-16,GABARAP,and LC3) and four Atg4 homologs (Atg4A/autophagin-2,Atg4B/autophagin-1,Atg4C/autophagin-3,and Atg4D/autophagin-4). |
分子量 |
45KD |
同型 |
IgG |
GeneID |
115201 |
理论分子量 |
45KD |
SWISS |
Q8WYN0 |
宿主物种 |
Rabbit |
免疫原 |
Recombinant Protein |
克隆性 |
Polyclonal |