产品名称 |
CD10 Rabbit Polyclonal Antibody(CD10) |
反应种属 |
H,M,R |
应用 |
IHC |
配方 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
别称 |
CALLA,Enkephalinase,MME,NEP,Neutral endopeptidase antibody |
储存 |
Store at -20°C. Stable for one year from the date of shipment. |
推荐稀释比 |
IHC 1:200-500 |
特异性 |
Antibody can detect endogenous CD10 proteins. |
背景信息 |
CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides,most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein,the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons,neprilysin is regulated by the protein nicastrin,a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta. |
分子量 |
85KD |
同型 |
IgG |
GeneID |
4311 |
理论分子量 |
85KD |
SWISS |
P08473 |
宿主物种 |
Rabbit |
免疫原 |
Recombinant Protein |
克隆性 |
Polyclonal |