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| 产品名称 | CK16 Mouse Monoclonal Antibody (6F6) | 反应种属 | H,M,R |
| 应用 | IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | N/A | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | IHC 1:200 | ||
| 特异性 | Antibody can detect endogenous CK16 proteins. | ||
| 背景信息 | Keratin 16 is expressed in keratinocytes,which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly,a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins,but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation,and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. | ||
| 分子量 | 51KD | 同型 | IgG1 |
| GeneID | 3868 | 理论分子量 | 51KD |
| SWISS | P08779 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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IHC staining of human gullet cancer tissue with CK16 mouse mAb diluted at 1:200.