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| 产品名称 | TFE3 Mouse Monoclonal Antibody(5B10) | 反应种属 | H |
| 应用 | IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | BHLHE33,Transcription factor E3,Class E basic helix-loop-helix protein 33,bHLHe33 | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | IHC 1:100-200 | ||
| 特异性 | Antibody can detect endogenous TFE3 proteins. | ||
| 背景信息 | transcription factor binding to IGHM enhancer 3(TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers,resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma),NONO (non-POU domain containing,octamer-binding),and ASPSCR1 (alveolar soft part sarcoma chromosome region,candidate 1),among other genes. | ||
| 分子量 | 62KD | 同型 | IgG1 |
| GeneID | 7030 | 理论分子量 | 62KD |
| SWISS | P19532 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Esophageal Squamous Cell Carcinoma Tissue using TFE3 Mouse mAb diluted at 1:200.