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| 产品名称 | COX2 Cyclooxygenase 2 Mouse Monoclonal Antibody(3D4) | 反应种属 | H,M,R |
| 应用 | IHC | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | IHC 1:50-100 | ||
| 特异性 | Antibody can detect endogenous COX2 proteins. | ||
| 背景信息 | Prostaglandin-endoperoxide synthase 2,also known as cyclooxygenase-2 or simply COX-2,is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described. | ||
| 分子量 | 74KD | 同型 | IgG1 |
| GeneID | 5743 | 理论分子量 | 70KD |
| SWISS | P35354 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using COX2/Cyclooxygenase 2 Mouse mAb diluted at 1:100.