产品名称 |
Cofilin 1 Rabbit Polyclonal Antibody(CFL1) |
反应种属 |
H,M,R |
应用 |
WB |
配方 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
别称 |
CFL1,CFL,Cofilin-1,18 KD a phosphoprotein,p18,Cofilin,non-muscle isoform |
储存 |
Store at -20°C. Stable for one year from the date of shipment. |
推荐稀释比 |
WB 1:2,000-5,000 |
特异性 |
Antibody can detect endogenous Cofilin proteins. |
背景信息 |
Cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
分子量 |
19KD |
同型 |
IgG |
GeneID |
1072 |
理论分子量 |
~19KD |
SWISS |
P23528 |
宿主物种 |
Rabbit |
免疫原 |
Recombinant Protein |
克隆性 |
Polyclonal |