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| 产品名称 | P63-α Mouse Monoclonal Antibody(6E12) | 反应种属 | H,M,R |
| 应用 | WB | ||
| 配方 | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. | ||
| 别称 | p63,Tumor protein 63 antibody,p53CP | ||
| 储存 | Store at -20°C. Stable for one year from the date of shipment. | ||
| 推荐稀释比 | WB 1:1,000-2,000 | ||
| 特异性 | Antibody can detect endogenous P63-αproteins. | ||
| 背景信息 | p63 can induce p53-responsive genes and apoptosis,mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung,head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain,and alternative splicing at the carboxy-terminus yields the α,β,and γ isoforms . | ||
| 分子量 | 50-80KD | 同型 | IgG1 |
| GeneID | 8626 | 理论分子量 | 50-80KD |
| SWISS | Q9H3D4 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Western blot analysis of 1)A431 Cell Lysate, 2)3T3 Cell Lysate , 3)PC-12 Cell Lysate using P63-α Mouse mAb diluted at 1:2000.